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Thermal response of steel framing members in open car park fires

Xia YAN; Marion CHARLIER; Thomas GERNAY

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 9, Pages 1071-1088 doi: 10.1007/s11709-022-0879-0

Abstract: For open car park structures, adopting a performance-based structural fire design is often justifiedthis design approach requires an accurate assessment of temperatures in structural members exposed to carThis paper describes a numerical study on the thermal exposure on steel framing members in open car parkResults show that temperatures in unprotected beams and columns are influenced by the section geometry, car

Keywords： open car park localized fire steel frame numerical modeling computational fluid dynamics

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The Status and Problems in Developing Private Use Car for China

Guo Konghui

Strategic Study of CAE 2000, Volume 2, Issue 8, Pages 25-30

Abstract:

Should China develop its private use car? What kind of passenger car should China develop?Should China develop its own passenger car industry?What is the way out for China´s passenger car industry?And how to develop Chinese passenger car industry?to solve the“auto disaster”problems is not to put more restrains on the use of private car

Keywords： Chinese auto industry private use car family use car state and problems

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Design and analyses of open-ended pipe piles in cohesionless soils

Yuan GUO,Xiong (Bill) YU

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 1, Pages 22-29 doi: 10.1007/s11709-016-0314-5

Abstract: Large open-ended pipe pile has been found to be advantageous for use in transportation projects.To close this practice gap, this paper first summarized different design methods for open-ended pipe

Keywords： open-ended pipe pile soil plug DEM base capacity

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Development of a cloud condensation nuclei (CCN) counter using a laser and charge-coupled device (CCD) camera

Mikyung PARK, Jinkwan OH, Kihong PARK

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 3, Pages 313-319 doi: 10.1007/s11783-011-0346-y

Abstract: A continuous flow streamwise thermal gradient cloud condensation nuclei (CCN) counter with an aerosol focusing and a laser-charge-coupled device (CCD) camera detector system was developed here. The counting performance of the laser-CCD camera detector system was evaluated by comparing its measured number concentrations with those measured with a condensation particle counter (CPC) using polystyrene latex (PSL) and NaCl particles of varying sizes. The CCD camera parameters (e.g. brightness, gain, gamma, and exposure time) were optimized to detect moving particles in the sensing volume and to provide the best image to count them. The CCN counter worked well in the particle number concentration range of 0.6–8000 #·cm and the minimum detectable size was found to be 0.5 μm. The supersaturation in the CCN counter with varying temperature difference was determined by using size-selected sodium chloride particles based on K?hler equation. The developed CCN counter was applied to investigate CCN activity of atmospheric ultrafine particles at 0.5% supersaturation. Data showed that CCN activity increased with increasing particle size and that the higher CCN activation for ultrafine particles occurred in the afternoon, suggesting the significant existence of hygroscopic or soluble species in photochemically-produced ultrafine particles.

Keywords： aerosol cloud condensation nuclei (CCN) counter ultrafine particle

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CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells

Yongping Zhang, Xingying Zhang, Chen Cheng, Wei Mu, Xiaojuan Liu, Na Li, Xiaofei Wei, Xiang Liu, Changqing Xia, Haoyi Wang

Frontiers of Medicine 2017, Volume 11, Issue 4, Pages 554-562 doi: 10.1007/s11684-017-0543-6

Abstract:

T cells engineered with chimeric antigen receptor (CAR) have been successfully applied to treat advancedThe immunosuppressive nature of tumor microenvironment is considered one of the key factors limiting CAR-TWe successfully generated LAG-3 knockout T and CAR-T cells with high efficiency using LAG-3 knockout CAR-T cells displayed robust antigen-specific antitumor activity incell culture and in murine xenograft model, which is comparable to standard CAR-T cells.

Keywords： CAR-T CRISPR-Cas9 LAG-3

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Electric Car Market Poised to Accelerate

Chris Palmer

Engineering 2021, Volume 7, Issue 2, Pages 136-138 doi: 10.1016/j.eng.2020.12.009

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NC flame pipe cutting machine tool based on open architecture CNC system

Xiaogen NIE, Yanbing LIU

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 2, Pages 147-152 doi: 10.1007/s11465-009-0025-x

Abstract: The paper deals with the design and implementation of an open architecture CNC system for the NFPCM,Further, the paper develops the program and sets up the open and module NC system.

Keywords： flame pipe cutting flame incision tracks CNC open architecture CNC system

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CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies

Frontiers of Medicine 2021, Volume 15, Issue 6, Pages 783-804 doi: 10.1007/s11684-021-0904-z

Abstract: Chimeric antigen receptor T-cell (CAR T) immunotherapy opens a new path for targeted therapy of hematologicalIn this review, through a representative case study, we summarize the current experience of CAR T-celleffects, the causative mechanisms of therapy resistance, and new strategies to improve the efficacy of CAR

Keywords： CAR T cells hematological malignancies review

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Cavitation in semi-open centrifugal impellers for a miniature pump

LUO Xianwu, LIU Shuhong, ZHANG Yao, XU Hongyuan

Frontiers in Energy 2008, Volume 2, Issue 1, Pages 31-35 doi: 10.1007/s11708-008-0011-8

Abstract: Cavitation in miniature pumps was investigated experimentally for two semi-open centrifugal impellerssimilar cavitation performances as an ordinary-size pump, with the cavitation performance of the semi-openAlso, both the hydraulic and cavitation performance of the semi-open impeller were improved by the leaned

Keywords： cavitation performance semi-open impeller increased two-dimensional efficiency

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Characterization of hidden rules linking symptoms and selection of acupoint using an artificial neural network model

Won-Mo Jung, In-Soo Park, Ye-Seul Lee, Chang-Eop Kim, Hyangsook Lee, Dae-Hyun Hahm, Hi-Joon Park, Bo-Hyoung

Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 112-120 doi: 10.1007/s11684-017-0582-z

Abstract: Comprehension of the medical diagnoses of doctors and treatment of diseases is important to understand the underlying principle in selecting appropriate acupoints. The pattern recognition process that pertains to symptoms and diseases and informs acupuncture treatment in a clinical setting was explored. A total of 232 clinical records were collected using a Charting Language program. The relationship between symptom information and selected acupoints was trained using an artificial neural network (ANN). A total of 11 hidden nodes with the highest average precision score were selected through a tenfold cross-validation. Our ANN model could predict the selected acupoints based on symptom and disease information with an average precision score of 0.865 (precision, 0.911; recall, 0.811). This model is a useful tool for diagnostic classification or pattern recognition and for the prediction and modeling of acupuncture treatment based on clinical data obtained in a real-world setting. The relationship between symptoms and selected acupoints could be systematically characterized through knowledge discovery processes, such as pattern identification.

Keywords： acupuncture indication neural network pattern identification prediction

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The engineering and technology progress of CAR-CA

Zhao Qinping

Strategic Study of CAE 2009, Volume 11, Issue 10, Pages 25-31

Abstract: To meet the requirement of the design and manufacture of commercial aircraft in China, CAR-CA(collaborativeThis paper introduced the engineering and technology progress of CAR-CA, including the system architecture

Keywords： augmented reality collaboration cockpit design maintenance

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Characteristics of pollutants behavior in a stormwater constructed wetland during dry days

Jianghua YU, Kisoo PARK, Youngchul KIM

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5, Pages 649-657 doi: 10.1007/s11783-012-0426-7

Abstract: A stormwater wetland treating non-point source pollution (NPS) from a 64 ha agricultural watershed was monitored over a period of five months. The results indicated that pH and dissolved oxygen (DO) were increased in the wetland due to the algal growth. The highest total suspended solids (TSS) concentration was observed in the aeration pond due to the resuspension of solids, decreased in the wetland. The respective decreases in total nitrogen (TN) and total kjeldahl nitrogen (TKN) were 15.9% and 28.7% on passing through the wetland. The nitrate and ammonia were increased by 45.4% and decreased by 79.9%, respectively. These variations provided strong evidence for the existence of nitrification. The total phosphorus (TP) and phosphate had respective reductions of 52.3% and 58.2% over the wetland. The total chemical oxygen demand (TCOD) and soluble chemical oxygen demand (SCOD) were also decreased. Generally, the TN, TP and phosphate removal efficiencies were positive. These positive removal efficiencies were mainly due to microbial activities, uptake by plants, and chemical precipitation at high pH. Negative removal efficiencies can be caused by continuous rainfall activities, with short antecedent dry days (ADDs) and unstable hydraulic conditions, some other biogeochemical transformations and algal growth also being important parameters.

Keywords： constructed stormwater wetland dry days nitrification and denitrification pollutants characteristic

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Drivers and barriers to engage enterprises in environmental management initiatives in Suzhou Industrial Park

Bing ZHANG, Jun BI, Beibei LIU

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 2, Pages 210-220 doi: 10.1007/s11783-009-0014-7

Abstract: Therefore, this research takes the enterprises in Suzhou Industrial Park, China as the case study to

Keywords： small- and medium-sized enterprises (SMEs) environmental management initiative Suzhou industrial park

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Experience and Inspiration from Construction of United States National Parks and Gateway Communities

Liu Huiliang

Strategic Study of CAE 2016, Volume 18, Issue 5, Pages 100-108 doi: 10.15302/J-SSCAE-2016.05.014

Abstract:

This year is the one-hundredth-year anniversary of the United States National Park Service (US NPSOver the last one hundred years, the national park system of the United States had become an importantthe discussion on the interdependent relationship between the gateway communities and the national parkThis paper uses Rocky Mountain National Park (RMNP) and the town of Estes Park, RNMP's main gateway

Keywords： US National Park Service gateway communities Rocky Mountain National Park the town of Estes Park

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Evaluation of the harmonic scalpel in open surgery for abdominal aortic aneurysm

Zeyu Wu, Zhe Chen, Lin Peng

Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 85-88 doi: 10.1007/s11684-012-0174-x

Abstract: During the last few years, many surgeons have begun to use the harmonic scalpel in open surgery.The aim of the present study is to determine the value of the harmonic scalpel in open operation forA total of 153 patients who underwent open surgery for AAA at the Department of Vascular Surgery of GuangdongOpen surgery performed with the harmonic scalpel on 105 patients was compared with open operation usingThe harmonic scalpel is a safe and minimally invasive tool in open surgery for AAA and is associated

Keywords： abdominal aortic aneurysm harmonic scalpel minimally invasive